A biopsy of the thyroid gland is generally performed to evaluate one of the following:
- A palpable nodule within the thyroid gland.
- A nodule which is not as active as the rest of the thyroid gland on a nuclear medicine scan (a “cold” nodule).
- A nodule which appears solid on ultrasound.
All of these can generally be diagnosed by performing a biopsy under ultrasound guidance.